Typhoid fever is a significant infectious disease caused by Salmonella typhi bacteria, which shares similarities with the bacteria responsible for food poisoning. It is easily transmitted through contaminated water or food and annually affects a considerable number of individuals, ranging from 11 to 20 million cases. ​ In the United Kingdom, tropical illnesses like typhoid fever are relatively rare, with only 300 confirmed infections per year. However, when traveling abroad, it is crucial to ascertain the prevalence of the infection in your destination. Typhoid fever is most commonly found in regions such as India, Asia, Africa, and South America, as well as in countries with limited access to clean water sources. ​ When planning your travel, it is important to be well-informed about the likelihood of encountering typhoid fever in your specific destination. By staying vigilant and taking necessary precautions, you can minimize the risk of contracting this disease and ensure a safe and healthy journey.

Typhoid fever can be easily transmitted from person to person. The bacteria responsible for the infection are primarily spread through faeces or, in some cases, urine, which can contaminate food and water due to inadequate sanitation practices. If an infected individual handles food without practicing proper hand hygiene after using the toilet, they can pass on typhoid fever to others. Similarly, individuals who share restroom facilities and neglect to wash their hands increase their risk of contracting the infection. ​ Furthermore, in regions with limited sanitation, infected human waste can contaminate the water supply. This contamination can be transmitted through the consumption of contaminated drinking water, the washing of food, or the consumption of seafood obtained from polluted water sources. ​ Maintaining good hand hygiene is essential for protecting yourself against typhoid fever. It is crucial to use antibacterial hand wash and thoroughly clean both the front and back of your hands for a minimum of 20 seconds. By practicing proper hand hygiene, you can significantly reduce the risk of contracting and spreading typhoid fever

Typically, the symptoms of typhoid fever manifest approximately 1 to 2 weeks following the contraction of the infection. When promptly treated, these symptoms generally show improvement within 3 to 5 days. However, without the administration of antibiotics, they can persist for weeks or even months. Symptoms of typhoid can include: High Fever: Sustained and persistent high fever is a hallmark symptom of typhoid fever. Abdominal Pain: Intense abdominal discomfort, often located in the lower right quadrant, is frequently experienced. Headaches: Severe headaches are a typical symptom, often accompanied by general body pain and muscle aches. Weakness and Fatigue: Feeling exhausted and lacking energy is a common occurrence during typhoid fever. Loss of Appetite: A significant decrease in appetite and subsequent weight loss can be observed. Diarrhoea or Constipation: Changes in bowel movements, ranging from diarrhoea to constipation, may be present. Rose Spots: Pink, raised rashes known as "rose spots" can appear on the trunk of the body. Mental Confusion: In some cases, individuals with typhoid fever may experience mental confusion or delirium. It is important to note that these symptoms can vary in severity and may not be present in all cases of typhoid fever. If you suspect you or someone else may have typhoid fever, it is crucial to seek medical attention for proper diagnosis and treatment.

Typhoid fever is typically managed with antibiotics, which can be administered at home. However, if symptoms worsen and become severe, hospitalization may be necessary. If diagnosed early, a course of antibiotic tablets lasting 7 to 14 days is usually prescribed. Improvement in symptoms is often observed within 5 days of starting the treatment. In addition to antibiotic therapy, samples of blood, stool, or urine may be collected to identify the specific strain of Salmonella typhi causing the infection. Certain strains may be more resistant to antibiotics, and in such cases, an injection may be required. During recovery from typhoid fever, it is important to prioritize rest and maintain a regular eating schedule. Adequate hydration should be ensured by consuming plenty of fluids or using rehydration treatments. If symptoms worsen or new symptoms arise, it is crucial to contact a healthcare provider promptly. Even after recovery, it is essential to continue practicing good hand hygiene and personal cleanliness to minimize the risk of transmitting typhoid fever to others. Avoid preparing food for others and follow your doctor's advice regarding testing for any remaining bacteria before returning to normal activities.

While getting vaccinated provides some protection against typhoid fever, it does not guarantee complete immunity. To minimize the risk of infection, it is important to follow these preventive measures: Consume only bottled water that is properly sealed. Opt for pasteurized milk and avoid raw milk products. Refrain from using ice in beverages. Boil water or use a disinfectant obtained from a pharmacy to treat water. Thoroughly wash and peel fruits, vegetables, and other food items. Practice proper hand hygiene by washing hands thoroughly after using the toilet, touching animals, or interacting with others (e.g., shaking hands). Avoid consuming potentially contaminated foods such as seafood and salads. In summary, typhoid fever is a severe tropical illness caused by the bacteria Salmonella typhi. It is prevalent in Africa, India, South America, parts of Asia (including China), and can be life-threatening if left untreated. If you experience symptoms such as high temperature, headaches, fatigue, or constipation, it is crucial to seek medical attention immediately. Antibiotics are commonly used for treatment, but vaccination is the most effective preventive measure against typhoid fever.

The top countries/regions where typhoid fever is commonly found include: South Asia: Countries in South Asia, such as India, Pakistan, Bangladesh, and Nepal, have a high prevalence of typhoid fever. Southeast Asia: Several countries in Southeast Asia, including Indonesia, Vietnam, Cambodia, and the Philippines, have a significant burden of typhoid fever. Sub-Saharan Africa: Regions in Sub-Saharan Africa, including Nigeria, Kenya, Ghana, and Sudan, experience a high number of typhoid fever cases. Central and South America: Countries in Central and South America, such as Mexico, Peru, Colombia, and Brazil, have a notable incidence of typhoid fever. Middle East: Certain countries in the Middle East, such as Iraq, Saudi Arabia, and Yemen, have reported cases of typhoid fever. It is important to note that typhoid fever can occur in other regions as well, but these areas have a higher incidence due to factors like inadequate sanitation, limited access to clean water, and population density. Travelers to these regions should take necessary precautions, including vaccination and practicing good hygiene, to reduce the risk of contracting typhoid fever.